Aging rewires skin cells to amplify inflammation in aged mice
Researchers linked aging skin inflammation to BMAL1 and YAP, two proteins that activate inflammatory genes.
Diagnósticos, prótesis, vacunas, genómica: la medicina que gana años de vida.
La medicina que gana años de vida: cribados asistidos por IA que examinan a millones de pacientes, vacunas de nueva generación, una genómica que pasa de la secuenciación al tratamiento, prótesis e implantes que devuelven capacidades perdidas. La sección sigue los ensayos clínicos concluidos, las autorizaciones de comercialización, los despliegues hospitalarios — el momento en que una tecnología deja de ser una publicación para convertirse en un cuidado.
Las cifras mandan: cohortes, tasas de detección, mortalidad evitada, costes. Cubrimos con gusto los sistemas de salud que despliegan a gran escala —India, Brasil, el Sudeste Asiático— porque las tecnologías frugales suelen probarse allí antes de llegar a otros lugares. Cada artículo se apoya en el ensayo, la autorización o el estudio que lo funda, y los cita.
Researchers linked aging skin inflammation to BMAL1 and YAP, two proteins that activate inflammatory genes.
Intismeran was tested with Keytruda in 1,137 people after surgery for high-risk melanoma.
Ten patients received about 100 million lab-grown heart cells during bypass surgery.
Australian data show vaccination during pregnancy protected babies from RSV-related hospitalization through six months of life.
TKa levels were measured in 81 patients with BRAF-mutated metastatic melanoma.
The molecules reduced lung, breast cancer and melanoma cell viability in laboratory tests.
Columbia’s EWI scan mapped delayed activation near the mitral valve in pediatric patients.
Nine patients received the treatment in a first-in-human trial at Moorfields Eye Hospital and UCL.
University of Pittsburgh researchers tracked LAG3-marked T cells after they left melanoma tumors in mice.
The resource combines genomic and clinical data from 36 pediatric studies.
UVA Health found anesthesia, surgery and intensive-care stress disrupted memory and sleep systems in aged mice.
The method compares the two largest aldosterone-producing nodules in removed adrenal tissue.
The chip combines each patient's tumor cells with the surrounding blood-vessel barrier.
Decision tools helped clinicians test less often when ventilated children showed no signs of respiratory infection.
A*STAR researchers in Singapore used organoids to map how autism-linked developmental changes vary across brain tissue.
The work remains preclinical, using human cells, organoids and laboratory models.
CREW was designed for women with cardiovascular disease in rural and remote communities.
A CDC and Emory study found the benefit across six high-burden countries using routine HIV program data.