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NAT10’s helicase domain fuels tumor growth in lab and animal models
Northwestern researchers tested more than 1,900 NAT10 variants in one proliferation assay.
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Diagnosi, protesi, vaccini, genomica: la medicina che guadagna anni di vita.
Northwestern researchers tested more than 1,900 NAT10 variants in one proliferation assay.
L-32 targets PTPN22, a protein that restrains immune activity.
The combination pushed tumor-cell DNA damage beyond repair, triggering programmed cell death.
WashU researchers found lymph node-like structures in the skull marrow of mice and evidence of similar cells in humans.
The work remains preclinical, using human cells, organoids and laboratory models.