Diagnosi, protesi, vaccini, genomica: la medicina che guadagna anni di vita.
La medicina che guadagna anni di vita: screening assistiti dall’IA che esaminano milioni di pazienti, vaccini di nuova generazione, una genomica che passa dal sequenziamento alla terapia, protesi e impianti che restituiscono capacità perdute. La rubrica segue le sperimentazioni cliniche concluse, le autorizzazioni all’immissione in commercio, le adozioni ospedaliere — il momento in cui una tecnologia smette di essere una pubblicazione per diventare una cura.
I numeri comandano: coorti, tassi di rilevamento, mortalità evitata, costi. Copriamo volentieri i sistemi sanitari che adottano su larga scala — l’India, il Brasile, il Sud-est asiatico — perché le tecnologie frugali si mettono spesso alla prova lì prima di arrivare altrove. Ogni articolo si appoggia alla sperimentazione, all’autorizzazione o allo studio che lo fonda, e li cita.
I ricercatori della Marshall University hanno bloccato un segnale delle cellule adipose, riducendo la placca e l’infiammazione dei vasi nei topi.
University of Utah researchers tested the approach in mouse models and human liver organoids.
Rice University and ETH Zurich grew human sensory neurons with Schwann cells, which form the myelin coating around nerve fibers.
The University of Liège team mapped 11 stress proteins in human joint tissues from people with inflammatory diseases.
Hokkaido University researchers tracked odors linked to water, air puffs or nothing.
The University of Virginia team found 69.8% of patients had metastatic disease, including aggressive cancers such as pancreatic cancer.
Boston University researchers identified lung-vein cells that become active after injury and promote scar formation.
After three months of treatment, abnormal tau in the hippocampus fell by about 46%, while tau in the cerebrospinal fluid more than doubled.
Tohoku University researchers stimulated the vagus nerve after training, not during it, in a mouse eye-movement task.
University of Alberta researchers created SNAP, a drug based on a molecule found in hibernating snails.
The University of Michigan team turned a gut-bacteria metabolite into an oral nano-delivered prodrug.
Researchers at Washington University tested a skin patch that samples fluid without drawing blood.
Researchers at National Taiwan University built the first spatial map of ovarian clear cell carcinoma.
The SPAM questionnaire measures perceived spatial navigation and memory across a person's lifetime and recent months.
The University of Eastern Finland compared patient-derived microglia with cells from healthy controls.
University of Michigan researchers combined BET and DNMT inhibitors against prostate tumors that had changed cellular identity.
University of Missouri researchers used Torin 2 to enhance autophagy, the cell’s cleanup and recycling process.
Washington University researchers developed NGSE-Corr to compare imaging tools when the true measurement is unknown.