Diagnosi, protesi, vaccini, genomica: la medicina che guadagna anni di vita.
La medicina che guadagna anni di vita: screening assistiti dall’IA che esaminano milioni di pazienti, vaccini di nuova generazione, una genomica che passa dal sequenziamento alla terapia, protesi e impianti che restituiscono capacità perdute. La rubrica segue le sperimentazioni cliniche concluse, le autorizzazioni all’immissione in commercio, le adozioni ospedaliere — il momento in cui una tecnologia smette di essere una pubblicazione per diventare una cura.
I numeri comandano: coorti, tassi di rilevamento, mortalità evitata, costi. Copriamo volentieri i sistemi sanitari che adottano su larga scala — l’India, il Brasile, il Sud-est asiatico — perché le tecnologie frugali si mettono spesso alla prova lì prima di arrivare altrove. Ogni articolo si appoggia alla sperimentazione, all’autorizzazione o allo studio che lo fonda, e li cita.
Researchers linked aging skin inflammation to BMAL1 and YAP, two proteins that activate inflammatory genes.
Intismeran was tested with Keytruda in 1,137 people after surgery for high-risk melanoma.
Ten patients received about 100 million lab-grown heart cells during bypass surgery.
Australian data show vaccination during pregnancy protected babies from RSV-related hospitalization through six months of life.
TKa levels were measured in 81 patients with BRAF-mutated metastatic melanoma.
The molecules reduced lung, breast cancer and melanoma cell viability in laboratory tests.
Columbia’s EWI scan mapped delayed activation near the mitral valve in pediatric patients.
Nine patients received the treatment in a first-in-human trial at Moorfields Eye Hospital and UCL.
University of Pittsburgh researchers tracked LAG3-marked T cells after they left melanoma tumors in mice.
The resource combines genomic and clinical data from 36 pediatric studies.
UVA Health found anesthesia, surgery and intensive-care stress disrupted memory and sleep systems in aged mice.
The method compares the two largest aldosterone-producing nodules in removed adrenal tissue.
The chip combines each patient's tumor cells with the surrounding blood-vessel barrier.
Decision tools helped clinicians test less often when ventilated children showed no signs of respiratory infection.
A*STAR researchers in Singapore used organoids to map how autism-linked developmental changes vary across brain tissue.
The work remains preclinical, using human cells, organoids and laboratory models.
CREW was designed for women with cardiovascular disease in rural and remote communities.
A CDC and Emory study found the benefit across six high-burden countries using routine HIV program data.