Diagnosi, protesi, vaccini, genomica: la medicina che guadagna anni di vita.
La medicina che guadagna anni di vita: screening assistiti dall’IA che esaminano milioni di pazienti, vaccini di nuova generazione, una genomica che passa dal sequenziamento alla terapia, protesi e impianti che restituiscono capacità perdute. La rubrica segue le sperimentazioni cliniche concluse, le autorizzazioni all’immissione in commercio, le adozioni ospedaliere — il momento in cui una tecnologia smette di essere una pubblicazione per diventare una cura.
I numeri comandano: coorti, tassi di rilevamento, mortalità evitata, costi. Copriamo volentieri i sistemi sanitari che adottano su larga scala — l’India, il Brasile, il Sud-est asiatico — perché le tecnologie frugali si mettono spesso alla prova lì prima di arrivare altrove. Ogni articolo si appoggia alla sperimentazione, all’autorizzazione o allo studio che lo fonda, e li cita.
The University of Liège team mapped 11 stress proteins in human joint tissues from people with inflammatory diseases.
The effect depends on MTDH in both liver cells and CD8+ T cells, not either cell type alone.
The MUSC team weakened resistant cancer cells before blocking their backup survival pathway.
The score combines biological sex with blood biomarkers linked to stress responses and plaque stability.
Antisense RNA delivered with nanoparticles blocked Smyca's activity in tumors and improved responses to existing treatments.
Hokkaido University researchers tracked odors linked to water, air puffs or nothing.
The registry-based trial covered 17,095 Swedish adults, including patients often excluded from conventional trials.
The B7-H3-targeting treatment was tested in 15 patients whose cancers resisted standard therapies.
- The target is a uORF, an upstream RNA start site that can divert ribosomes; inactivation lowers KCNQ2 mRNA levels.
Two Canadian trials followed 1,115 pacemaker and ICD patients across 13 centers for 18 months.
The vaccine was tested after melanoma had been surgically removed.
Ezplaz can be stored at room temperature for 12 months and reconstituted in about 2.5 minutes.
The model draws on individual data from 38,753 participants in nine major heart-failure trials.
USC's flexible MRI coils fit infants more closely than adult-sized equipment.
In mice, galectin-1 strengthened lung immunity when added to an experimental nasal flu vaccine.
The UK trial followed 2,234 people across 45 emergency departments after unexplained fainting.
The Nano-ERASER treatment helped support cells become new neurons in the brains of adult mice.
Participants had lost about 84% of their scalp hair before treatment began.