Digital trial doubles heart-failure drug starts in Denmark
A registry found untreated patients and offered a specialist telephone consultation through Denmark’s Digital Post system.
Diagnósticos, próteses, vacinas, genómica: a medicina que ganha anos de vida.
A medicina que ganha anos de vida: rastreios assistidos por IA que examinam milhões de doentes, vacinas de nova geração, uma genómica que passa da sequenciação ao tratamento, próteses e implantes que devolvem capacidades perdidas. A secção segue os ensaios clínicos concluídos, as autorizações de introdução no mercado, as implantações hospitalares — o momento em que uma tecnologia deixa de ser uma publicação para se tornar um cuidado.
Os números mandam: coortes, taxas de deteção, mortalidade evitada, custos. Cobrimos de bom grado os sistemas de saúde que implantam em grande escala — a Índia, o Brasil, o Sudeste Asiático — porque as tecnologias frugais costumam provar-se aí antes de chegarem a outros lugares. Cada artigo apoia-se no ensaio, na autorização ou no estudo que o funda, e cita-os.
A registry found untreated patients and offered a specialist telephone consultation through Denmark’s Digital Post system.
Medical rehabilitation is the clearest near-term business path for non-invasive brain-computer interfaces.
The phase 2 SHIELD-MI trial tested four intravenous doses around emergency angioplasty.
The PRAGUE-26 trial randomized 558 patients at 11 Czech sites to catheter therapy or anticoagulation alone.
The NEXAF trial tested eight supervised sessions followed by home exercise and digital monitoring.
The LAACS-2 trial found no significant overall reduction in stroke or transient ischemic attack.
The ongoing study covered 3,112 patients across 23 Swedish centers after type 1 heart attacks.
The randomized trial covered 1,507 adults with reduced-ejection-fraction heart failure across 22 Indian centers.
Researchers tested a 3–6 km/h treadmill pace, close to walking, at about 35% of peak oxygen uptake.
The AIR-STEMI trial enrolled 1,823 patients at 21 centers in Italy and Pakistan.
Rice University and ETH Zurich grew human sensory neurons with Schwann cells, which form the myelin coating around nerve fibers.
UChicago researchers mapped how tumor cells organize into spatial groups across 262 solid tumors.
The pathway was found in blood samples from children with hemolytic uremic syndrome.
The seven-year study involved 33,995 adults in 326 rural Chinese villages.
The drug occupied the same primary binding pocket as morphine, but used weaker hydrophobic interactions.
In 1,199 frail adults across 11 European countries, the intervention cut risk by 22% overall.
Hypoxanthine prompts gut cells to release serotonin, while butyrate makes their response stronger.
The oral drug was tested for 24 weeks in 375 patients across 57 centers in 10 countries.