Diagnósticos, próteses, vacinas, genómica: a medicina que ganha anos de vida.
A medicina que ganha anos de vida: rastreios assistidos por IA que examinam milhões de doentes, vacinas de nova geração, uma genómica que passa da sequenciação ao tratamento, próteses e implantes que devolvem capacidades perdidas. A secção segue os ensaios clínicos concluídos, as autorizações de introdução no mercado, as implantações hospitalares — o momento em que uma tecnologia deixa de ser uma publicação para se tornar um cuidado.
Os números mandam: coortes, taxas de deteção, mortalidade evitada, custos. Cobrimos de bom grado os sistemas de saúde que implantam em grande escala — a Índia, o Brasil, o Sudeste Asiático — porque as tecnologias frugais costumam provar-se aí antes de chegarem a outros lugares. Cada artigo apoia-se no ensaio, na autorização ou no estudo que o funda, e cita-os.
The University of Liège team mapped 11 stress proteins in human joint tissues from people with inflammatory diseases.
The effect depends on MTDH in both liver cells and CD8+ T cells, not either cell type alone.
The MUSC team weakened resistant cancer cells before blocking their backup survival pathway.
The score combines biological sex with blood biomarkers linked to stress responses and plaque stability.
Antisense RNA delivered with nanoparticles blocked Smyca's activity in tumors and improved responses to existing treatments.
Hokkaido University researchers tracked odors linked to water, air puffs or nothing.
The registry-based trial covered 17,095 Swedish adults, including patients often excluded from conventional trials.
The B7-H3-targeting treatment was tested in 15 patients whose cancers resisted standard therapies.
- The target is a uORF, an upstream RNA start site that can divert ribosomes; inactivation lowers KCNQ2 mRNA levels.
Two Canadian trials followed 1,115 pacemaker and ICD patients across 13 centers for 18 months.
The vaccine was tested after melanoma had been surgically removed.
Ezplaz can be stored at room temperature for 12 months and reconstituted in about 2.5 minutes.
The model draws on individual data from 38,753 participants in nine major heart-failure trials.
USC's flexible MRI coils fit infants more closely than adult-sized equipment.
In mice, galectin-1 strengthened lung immunity when added to an experimental nasal flu vaccine.
The UK trial followed 2,234 people across 45 emergency departments after unexplained fainting.
The Nano-ERASER treatment helped support cells become new neurons in the brains of adult mice.
Participants had lost about 84% of their scalp hair before treatment began.