No laboratório, IL-17A provoca dobramento precoce do córtex fetal
Investigadores da University of Aberdeen criaram cerebroides 3D a partir de tecido cortical humano em desenvolvimento.
Diagnósticos, próteses, vacinas, genómica: a medicina que ganha anos de vida.
A medicina que ganha anos de vida: rastreios assistidos por IA que examinam milhões de doentes, vacinas de nova geração, uma genómica que passa da sequenciação ao tratamento, próteses e implantes que devolvem capacidades perdidas. A secção segue os ensaios clínicos concluídos, as autorizações de introdução no mercado, as implantações hospitalares — o momento em que uma tecnologia deixa de ser uma publicação para se tornar um cuidado.
Os números mandam: coortes, taxas de deteção, mortalidade evitada, custos. Cobrimos de bom grado os sistemas de saúde que implantam em grande escala — a Índia, o Brasil, o Sudeste Asiático — porque as tecnologias frugais costumam provar-se aí antes de chegarem a outros lugares. Cada artigo apoia-se no ensaio, na autorização ou no estudo que o funda, e cita-os.
Investigadores da University of Aberdeen criaram cerebroides 3D a partir de tecido cortical humano em desenvolvimento.
Investigadores da Marshall University bloquearam um sinal das células adiposas, reduzindo a placa e a inflamação vascular em ratos.
University of Utah researchers tested the approach in mouse models and human liver organoids.
Rice University and ETH Zurich grew human sensory neurons with Schwann cells, which form the myelin coating around nerve fibers.
The University of Liège team mapped 11 stress proteins in human joint tissues from people with inflammatory diseases.
Hokkaido University researchers tracked odors linked to water, air puffs or nothing.
The University of Virginia team found 69.8% of patients had metastatic disease, including aggressive cancers such as pancreatic cancer.
Boston University researchers identified lung-vein cells that become active after injury and promote scar formation.
After three months of treatment, abnormal tau in the hippocampus fell by about 46%, while tau in the cerebrospinal fluid more than doubled.
Tohoku University researchers stimulated the vagus nerve after training, not during it, in a mouse eye-movement task.
University of Alberta researchers created SNAP, a drug based on a molecule found in hibernating snails.
The University of Michigan team turned a gut-bacteria metabolite into an oral nano-delivered prodrug.
Researchers at Washington University tested a skin patch that samples fluid without drawing blood.
Researchers at National Taiwan University built the first spatial map of ovarian clear cell carcinoma.
The SPAM questionnaire measures perceived spatial navigation and memory across a person's lifetime and recent months.
The University of Eastern Finland compared patient-derived microglia with cells from healthy controls.
University of Michigan researchers combined BET and DNMT inhibitors against prostate tumors that had changed cellular identity.
University of Missouri researchers used Torin 2 to enhance autophagy, the cell’s cleanup and recycling process.