Aging rewires skin cells to amplify inflammation in aged mice
Researchers linked aging skin inflammation to BMAL1 and YAP, two proteins that activate inflammatory genes.
Diagnostics, prosthetics, vaccines, genomics: the medicine that adds years to a life.
Medicine that wins years of life: AI-assisted screening examining millions of patients, next-generation vaccines, genomics moving from sequencing to treatment, prosthetics and implants restoring lost abilities. The section follows completed clinical trials, market authorisations, hospital roll-outs — the moment a technology stops being a paper and becomes care.
The numbers rule: cohorts, detection rates, avoided mortality, costs. We gladly cover the health systems deploying at scale — India, Brazil, Southeast Asia — because frugal technologies often prove themselves there before arriving anywhere else. Every article rests on the trial, authorisation or study behind it, and cites them.
Researchers linked aging skin inflammation to BMAL1 and YAP, two proteins that activate inflammatory genes.
Intismeran was tested with Keytruda in 1,137 people after surgery for high-risk melanoma.
Ten patients received about 100 million lab-grown heart cells during bypass surgery.
Australian data show vaccination during pregnancy protected babies from RSV-related hospitalization through six months of life.
TKa levels were measured in 81 patients with BRAF-mutated metastatic melanoma.
The molecules reduced lung, breast cancer and melanoma cell viability in laboratory tests.
Columbia’s EWI scan mapped delayed activation near the mitral valve in pediatric patients.
Nine patients received the treatment in a first-in-human trial at Moorfields Eye Hospital and UCL.
University of Pittsburgh researchers tracked LAG3-marked T cells after they left melanoma tumors in mice.
The resource combines genomic and clinical data from 36 pediatric studies.
UVA Health found anesthesia, surgery and intensive-care stress disrupted memory and sleep systems in aged mice.
The method compares the two largest aldosterone-producing nodules in removed adrenal tissue.
The chip combines each patient's tumor cells with the surrounding blood-vessel barrier.
Decision tools helped clinicians test less often when ventilated children showed no signs of respiratory infection.
A*STAR researchers in Singapore used organoids to map how autism-linked developmental changes vary across brain tissue.
The work remains preclinical, using human cells, organoids and laboratory models.
CREW was designed for women with cardiovascular disease in rural and remote communities.
A CDC and Emory study found the benefit across six high-burden countries using routine HIV program data.