Lab-grown human heart tissue links relaxation failure to inflammation
Researchers in Japan built a 3D human heart model of HFpEF, where the heart relaxes poorly despite normal contraction.
Diagnostics, prosthetics, vaccines, genomics: the medicine that adds years to a life.
Medicine that wins years of life: AI-assisted screening examining millions of patients, next-generation vaccines, genomics moving from sequencing to treatment, prosthetics and implants restoring lost abilities. The section follows completed clinical trials, market authorisations, hospital roll-outs — the moment a technology stops being a paper and becomes care.
The numbers rule: cohorts, detection rates, avoided mortality, costs. We gladly cover the health systems deploying at scale — India, Brazil, Southeast Asia — because frugal technologies often prove themselves there before arriving anywhere else. Every article rests on the trial, authorisation or study behind it, and cites them.
Researchers in Japan built a 3D human heart model of HFpEF, where the heart relaxes poorly despite normal contraction.
AEA kept rising through the marathon and remained elevated after 45 minutes of recovery.
Alternative splicing creates a longer kindlin-3 form that recruits more effectively to the cell membrane.
The model also showed less aggressive cells becoming mobile after they detached from neighboring cells and entered small tissue spaces.
The oral drug BI6674 reduced tumors in a genetically engineered mouse model.
Eleven left-hemisphere stroke patients were tested on familiar tool use and physical reasoning.
Pterostilbene, found in berries, boosted fat breakdown in cultured C2C12 mouse muscle cells.
The mice developed Rett-like breathing after MECP2 was blocked in oxygen-sensing cells beside the carotid artery.
The material combines more than 75% ceramic and zirconia filler by weight.
Penn Medicine’s phase 1 study is the first U.S. human test of conformal FLASH proton therapy.
ADAMTSL4 levels rose in mice and patients with colorectal or lung cancer who had cachexia.
The coding system scores praise, questions, commands and frustration in short recordings.
The clocks were built from 104,208 adults and 172 routine clinical indicators across three Chinese centers.
The result comes from aged mice, not human patients, and was reported in Nature Aging.
NTNU's model used age, sex and 60 health variables without seeing headache symptoms.
The atlas profiles 94,451 cells from children with Crohn’s disease and compares them with noninflammatory controls.
Two antibodies blocked allergic IgE from attaching to alpha-gal allergens in laboratory tests.
CondenScreen uses MLF2, a biomarker found across dysfunctional condensates, rather than disease-specific markers.