In the lab, 22 million immune cells map gene circuits
Gladstone, UCSF and Stanford switched off nearly 12,800 genes in human T cells from blood donors.
Diagnostics, prosthetics, vaccines, genomics: the medicine that adds years to a life.
Medicine that wins years of life: AI-assisted screening examining millions of patients, next-generation vaccines, genomics moving from sequencing to treatment, prosthetics and implants restoring lost abilities. The section follows completed clinical trials, market authorisations, hospital roll-outs — the moment a technology stops being a paper and becomes care.
The numbers rule: cohorts, detection rates, avoided mortality, costs. We gladly cover the health systems deploying at scale — India, Brazil, Southeast Asia — because frugal technologies often prove themselves there before arriving anywhere else. Every article rests on the trial, authorisation or study behind it, and cites them.
Gladstone, UCSF and Stanford switched off nearly 12,800 genes in human T cells from blood donors.
The FGF21–IGFBP1 signal was identified in laboratory and mouse studies.
The analysis covered 1,276 adults treated at 36 U.S. hospitals between 2014 and 2023.
Full pivotal data show aficamten improved patients’ symptoms and exercise capacity in nHCM.
The three-week NTNU study followed 51 participants and measured steps, game data, interviews and questionnaires.
Penn researchers found that SGLT2 inhibitors directly activate PANK1 in human heart cells.
Six people with treatment-refractory disease received the therapy at Charité in Berlin.
The CIMH studied people with alcohol dependence and adolescents receiving psychiatric treatment.
The injectable system held iodine-131 inside patient-derived keloid tissue for up to 14 days.
More than 36,000 matched adults were studied in each vaccine group in the U.S. comparison.
The model used five early clinical variables to estimate conversion within one year.
The grafts survived at least 81 days, formed blood vessels and flexed continuously without external stimulation.
KRIBB researchers modeled a patient-linked SPAST deletion in human brain organoids.
The map covers 100 high-confidence autism risk genes and finds that 87% of interactions were previously unknown.
FRACTURE-ML used Swedish records from 3,542,647 people aged 50 and older, followed for up to 10 years.
ASM4 neurons helped suppress aggression in grouped male and female fruit flies.
About 50% on keto no longer met prediabetes criteria, versus 29% on Mediterranean and 7% on plant-forward diets.
UCLA researchers studied 14,655 patient-drug pairs using three major cancer biologics.